this is such an interesting concept. would you keep the vampirism aspect? also would give you room to have someone bring edward back and be like, "hey babe i'm back" and your bella swan gets to have the satisfaction of telling him to take an intergalactic hike.
Nah, I'm setting her canon point during New Moon and Bella realizes she's an idiot teenager who was ready to make a decision that should absolutely not be made at 17. She's a human, and learning the advantages of being human. Since it's panfandom, I was debating having her know someone from the Imperium, but my only lined-up Imperium OC is a chaos-fallen Sororitas that actively shames her sisters because "actually, maybe things should change. maybe they'll be better." is open heresy.
But the idea of her being some sort of person immune to the eldritch horror of the world because she's effectively Soulless and cannot be impacted on that level seems like a really fun idea. And if Edward showed up, she'd probably just shrug and go "yeah that's the guy I wanted to date in high school" but now that she's 25, she doesn't really find a 17 year old boy physically or emotionally attractive. I'd probably want a Charlie more than any Cullens, or maybe even a grown-up Jacob.